The artist has donated the full amount of his £25,000 Mercury Prize cash to the MVT, which functions to preserve the United Kingdom's small music venues.
He was presented with the cheque on October 16 as his third album People Watching was declared the best record of the past year.
Fender has chosen to hand the money over to the trust, in appreciation of the vital role local spots had in his beginning days.
"As an artist wouldn't be doing this success if it weren't for all the shows I performed around the region, and elsewhere, when I was beginning," stated Sam Fender. "These locations are iconic, but they are facing challenges."
From early 2023 onward, more than 150 of these locations have permanently closed – about one-sixth of the total UK scene.
Recently, major artists like Pulp, the group Coldplay, the singer Katy Perry and Ed Sheeran have all aided the trust in its initiatives to support the industry, by adding a minor surcharge to their admission fees, which supports independent venues.
Fender also joined in, collecting in excess of £100,000 on his recent tour to assist 38 grassroots venues across the UK.
The money supported spaces that were facing possible closure due to difficulties stemming from water damage, fires and bereavements, as well as permit problems, court cases and noise complaints.
Additional spaces were granted financial assistance in improving infrastructure and gear that helped musicians and audiences.
"The idea that revenue from performances in big venues supports the independent spots, where it all starts for performers like me, is just common sense," Sam Fender has stated.
The musician is not the first artist to give his award prize money to good deeds.
When Pulp earned the award in the year 1996 for their record Different Class, lead singer Cocker stated that the act would donate their cash to the organization War Child.
During 2002, artist she split her award across a few good causes, including the NSPCC and a Sickle Cell organization.
"Additionally, I contributed a grand to Highgate Newtown, to their gymnastics class, because I trained in gymnastics when I was a child and they required new equipment," Ms Dynamite shared with outlets.
Previously, Ezra Collective donated their prize money to the community center that nurtured their band, alongside other independent music bodies.
Additionally the 1994 recipients the group donated their award to a multiple sclerosis charity after a close contact was identified with the illness.
"The victory was quite enough," stated vocalist the singer. "The prize was the bonus but we could do without the bonus, because we had the cake. So our success touched somebody else's life."
Last week, the MVT shared it had saved a couple of local spots in south-east England, by placing them under community ownership.
The first in Southampton and The Croft in the city were acquired under the community ownership initiative, which is supported by a national body and enthusiasts who acquire "stakes" in the properties.
